Hyaluronidase injections are used to remove unwanted hyaluronic acid (HA) based dermal filler material. Common examples of HA based dermal filler are the family of Juvederm and Restylane (e.g. Voluma, Vollure, Lyft, Refyne). Hyaluronidase is an enzyme that dissolves excessive quantities of injected HA, and subcutaneous nodules that can form after dermal filler injections. Hylenex and Vitrase are common brand names of Hyaluronidase used in Spa 35.